Platform Technology

The Kangti platform technology is a live cells screening system in which GPCRs are imbedded in the membrane of yeast cells and are able to maintain their normal functions in response to their cognate ligands. Upon introduction of a combinatorial antibody library into these cells, the antibody molecules capable of activating or inactivating the signal transduction of the GPCR are isolated.  This screening platform is robust and efficient, and it significantly increases the success rate in the identification of therapeutic antibody products. 

The Kangti’s antibody discovery system also has the ability to isolate antibodies that activate or inactivate the receptor in a G protein specific manner.